Protection against ischemia/reperfusion: role of the farnesol and red palm oil Summary of PhD Thesis
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منابع مشابه
The Role of Exercise Preconditioning in Cardioprotection against Ischemia Reperfusion Injury
Cardiovascular diseases are still the main cause of mortality around the world. Therefore, it is essential to develop practical means to reduce their burden. A wealth of evidence supports the role of physical exercise in attenuating many of the risk factors of cardiovascular diseases. Moreover, endurance training warrants protection against myocardial infarction. Exercise, even if performed ...
متن کاملDietary red palm oil supplementation protects against the consequences of global ischemia in the isolated perfused rat heart.
Activation of the NO-cGMP pathway is associated with myocardial protection against ischemia. During ischemia, function of this pathway is disturbed. Little is known about the effects of supplements such as Red Palm Oil (RPO) on the myocardial NO- cGMP- signalling pathway. RPO consists of saturated (SFAs), mono-unsaturated (MUFAs) and polyunsaturated (PUFAs) fatty acids and is an antioxidant ric...
متن کاملProtective Role of Elaesis guineensis Leaves against Crude Oil Tainted Diet–induced Hematotoxicity in Wistar Rats
Background: Crude oil is a very toxic chemical. Recently, the search for protective substances is attracting attention. This study aimed to investigate the hematoprotective potentials of oil palm leaves against the toxicity induced by crude oil. Methods: Male Wistar albino rats (n=36) were divided into six groups of rats (n=6). Group 1 (controls) were fed with normal rat food. Groups 2 and ...
متن کاملInhibition of Akt Attenuates RPO-Induced Cardioprotection
Previous studies have shown that red palm oil (RPO) supplementation protected rat hearts against ischaemia-reperfusion injury. Evidence from these studies suggested that Akt may be partly responsible for the observed protection. The aim of the current study was therefore to prove or refute the involvement of Akt in the RPO-induced cardioprotection by administration of a specific Akt inhibitor (...
متن کاملHealth benefits of a natural carotenoid rich oil: a proposed mechanism of protection against ischaemia/ reperfusion injury.
Numerous studies have reported the protective properties of carotenoid supplementation against skin and eye associated diseases. However, conflicting data concerning the efficacy of beta-carotene in the pathogenesis of cancers and cardiovascular disease exist. It has been shown that beta-carotene is an effective antioxidant on its own or in combination with other antioxidants. Red palm oil (RPO...
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